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位置: 首页 > 磷酸化抗体 > PLCgamma1(Phospho-Tyr783) Antibody

PLCgamma1(Phospho-Tyr783) Antibody#11103

PLCgamma1(Phospho-Tyr783) Antibody
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产品总价:
产品详情

产品名称PLCgamma1(Phospho-Tyr783) Antibody

来源种属Rabbit

克隆性Polyclonal

纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

应用WB

种属反应性Hu Ms Rt

特异性The antibody detects endogenous level of PLCg1 only when phosphorylated at tyrosine 783.

免疫原类型Peptide-KLH

免疫原描述Peptide sequence around phosphorylation site of tyrosine 783 (G-F-Y(p)-V-E) derived from Human PLCG1.

基因/蛋白名称PLCgamma1

修饰Phospho

别名Phosphoinositide phospholipase C; Phospholipase C-gamma-1;

数据库入口号Swiss-Prot: P19174
NCBI Protein: NP_002651.2

UniprotP19174

浓度1.0mg/ml

配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

应用详情

Predicted MW: 155kd
Western blotting: 1:500~1:1000
 

Western blot analysis of extracts from HL60 cells untreated or treated with EGF using PLCg1(Phospho-Tyr783) Antibody #11103.
背景

PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

DeBell KE, et al. Mol Cell Biol. 1999 Nov; 19(11): 7388-7398.
Ver

如果您使用该产品11103发表了文章,请通知我们,让我们可以引用您的文献。

et al,Synergistic effects of c-Jun and SP1 in the promotion of TGF尾1-mediated diabetic nephropathy progression.In Exp Mol Pathol on 2016 Jun by Pan Gao, Yingze Wei et al..PMID:27112839, , (2016),
PMID: 27112839
et al,Discovery of a novel inhibitor of the protein tyrosine phosphatase Shp2.In Sci Rep on 2015 Dec 2 by Chuan Chen , Mengmeng Cao et al..PMID: 26626996 , , (2015),
PMID: 26626996
et al,Antiproliferative Activity of Hinokitiol, a Tropolone Derivative, Is Mediated via the Inductions of p-JNK and p-PLC纬1 Signaling in PDGF-BB-Stimulated Vascular Smooth Muscle Cells.In Molecules on 2015 May 7 by Po-Sheng Yang, Meng-Jiy Wang et al..PMID: 25961161, , (2015),
PMID: 25961161
et al,Signal regulatory protein 伪 negatively regulates mast鈥恈ell activation following Fc蔚RI aggregation. In Eur J Immunol on 2013 Jun by Yu-fei Pan, Li-wei Dong, et al..PMID: 23504624, , (2013),
PMID: 23504624
Cheng-Ying Hsieh, Chien-Liang Liu, Ming-Jen Hsu et al,Inhibition of vascular smooth muscle cell proliferation of vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: Pivotal role of hydroxyl radical-mediated PLC娄脙1 and JAK2 phosphorylation., Free Radical Biology and Medicine, 49(5):881-893 (2010),
PMID: 20600839
et al,Inhibition of vascular smooth muscle cell proliferation by the vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: pivotal role of hydroxyl radical-mediated PLC纬1 and JAK2 phosphorylation. In Free Radic Biol Med on 2010 Sep 1 by Chien-Liang Liu, Ming-Jen Hsu, et al..PMID: 20600839, , (2010),
PMID: 20600839
5

注释

应用

  • WB免疫印迹
  • IHC免疫组化
  • IF免疫荧光
  • ICC免疫细胞化学
  • FC流式细胞
  • IP免疫沉淀
  • E酶联免疫吸附法
  • DB免疫斑点法
  • ChIP染色质免疫沉淀
  • GICA胶体金免疫层析法
  • NC阴性对照

种属反应性

  • Hu
  • Ms小鼠
  • Rt大鼠
  • Dm果蝇
  • C线虫
  • Mk
  • Rb
  • B
  • D
  • P
  • Hm仓鼠
  • ChHm中国仓鼠
  • Chk

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